Metformin Inhibits Proliferation of Human Thyroid Cancer TPC-1 Cells by Decreasing LRP2 to Suppress the JNK Pathway

Yang He,Lingling Cao,Li Wang,Lingping Liu,Ying Huang,Xuan Gong

Metformin Inhibits Proliferation of Human Thyroid Cancer TPC-1 Cells by Decreasing LRP2 to Suppress the JNK Pathway

2020

Yang He
Lingling Cao
Li Wang
Lingping Liu
Ying Huang
Xuan Gong

Objective To uncover the potential effect of metformin on proliferation and apoptosis of thyroid cancer TPC-1 cell line, and the underlying mechanism.

Keywords:

Cancer research
LRP2
Immunology
Metformin
Medicine
Thyroid cancer
JNK Pathway
Kinase
Apoptosis
Western blot
Cell culture
Viability assay

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