AVALIAÇÃO MORFOFUNCIONAL DE TRANSPLANTE OVARIANO AUTÓGENO NO RETROPERITÔNIO

Oophorectomy is required in many pelvic and abdominal procedures. Endocrine disturbances may be followed by severe systemic complications. Purpose: Aiming to keep the ovarian function after oophorectomy, the present study assessed the ovarian autotransplantation in the retroperitoneum. Material and Methods: Thirty-six cycling female Wistar rats were randomly divided in four groups: G1 (control) - sham operation; G2 - bilateral oophorectomy; G3 - bilateral oophorectomy and whole ovarium autotransplantation in the retroperitoneum; G4 - bilateral oophorectomy followed by sliced ovarium autotransplantation in the retroperitoneum. The estrous cycle was investigated in the third and sixth months. Histological studies of ovaries were carried out. Results: Animals from group G1 preserved the cycling sequence. Rats from group G2 remained in diestrus. In group G3, the vaginal smear of two rats showed an estrus pattern, three showed irregular cycles, and the remaining animals remained in diestrus. In group G4, rats showed irregular cycles, five presented normal cycle sequence and only one rat remained in diestrous. The histology indicated ovarian viability in Groups 3 and 4, and a better aspect in Group 4. Conclusions: Sliced ovarian autotransplantation in the retroperitoneum showed better morphofunction preservation.