Abstract 5136: Reduction in Myocardial Ischemia-reperfusion Injury in Group IV Cytosolic Phospholipase A2-deficient Mice Partly Due to Inhibition of TNFα-mediated Pathway to Cell Injury

Yukio Saito,Yousuke Watanabe,Hideto Mishina,Kazuhiro Watanabe,Toshiaki Yano,Tsuyoshi Kobayashi,Jun-ei Obata,Ken-ichi Kawabata,Takao Shimizu,Kiyotaka Kugiyama

Abstract 5136: Reduction in Myocardial Ischemia-reperfusion Injury in Group IV Cytosolic Phospholipase A2-deficient Mice Partly Due to Inhibition of TNFα-mediated Pathway to Cell Injury

2009

Yukio Saito
Yousuke Watanabe
Hideto Mishina
Kazuhiro Watanabe
Toshiaki Yano
Tsuyoshi Kobayashi
Jun-ei Obata
Ken-ichi Kawabata
Takao Shimizu
Kiyotaka Kugiyama

Type IV cytosolic phospholipase A2 (cPLA2), which preferentially cleaves arachidonic acid from phospholipids, plays an important role in tissue injury. The downstream signal in response to TNFα, a ...

Keywords:

Ischemia
Cell
Arachidonic acid
Tumor necrosis factor alpha
Cardiology
Diabetes mellitus
Phospholipase A2
Pharmacology
Internal medicine
Cytosol
Medicine
Reperfusion injury
deficient mouse
myocardial ischemia

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations