TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling

Paloma Bragado,Yeriel Estrada,Falguni Parikh,S Krause,Carla S. Capobianco,Hernán G. Farina,D Schewe,Julio A. Aguirre-Ghiso

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling

2013

Paloma Bragado
Yeriel Estrada
Falguni Parikh
S Krause
Carla S. Capobianco
Hernán G. Farina
D Schewe
Julio A. Aguirre-Ghiso

Aguirre-Ghiso and colleagues report that the intensity of TGF-β2 signalling dictates dormancy or metastatic growth of disseminated tumour cells by regulating the activity of p38α/β in different target organs.

Keywords:

Cell biology
Tumor microenvironment
Cancer
Transforming growth factor
Cell fate determination
Signal transduction
Enzyme activator
Metastasis
Cancer dormancy
Biology

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

273

Citations