The Convergence of Therapeutic Drug Monitoring and Pharmacogenetic Testing to Optimize Efavirenz Therapy

Salvador Cabrera Figueroa,María del Mar Fernández de Gatta,Lorena Hernández García,Alfonso Domínguez-Gil Hurlé,Carmen Bustos Bernal,Rosa Sepúlveda Correa,María José García Sánchez

The Convergence of Therapeutic Drug Monitoring and Pharmacogenetic Testing to Optimize Efavirenz Therapy

2010

Salvador Cabrera Figueroa
María del Mar Fernández de Gatta
Lorena Hernández García
Alfonso Domínguez-Gil Hurlé
Carmen Bustos Bernal
Rosa Sepúlveda Correa
María José García Sánchez

Abstract:The aim of this study was to show the benefits of combining therapeutic drug monitoring (TDM) and pharmacogenetic analyses to optimize efavirenz (EFV) therapy. Patients were selected to minimize nongenetic differences between patients: 32 HIV adherent patients without drug interactions trea

Keywords:

Therapeutic drug monitoring
Drug
Oncology
Anesthesia
Pharmacogenetics
Efavirenz
Reverse-transcriptase inhibitor
Pharmacology
Medicine
Internal medicine
medical screening
human immunodeficiency virus

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