Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice

In contrast to most other tissues in the body, adipose tissue con-stantly experiences expansion and shrinkage throughout adulthood because of changes in metabolic demand. The plasticity of WAT and BAT determines whether an individual phenotype is obese or lean. Obesity and its related metabolic disorders such as diabetes, cardio-vascular disease and cancer are among the leading causes of mortal-ity in adult humans in Western society and in most other parts of the world