Some New Coordination Compounds of Organosilicon(IV) with Schiff Bases of Sulpha Drugs

New hexa-coordinated complexes of organosilicon(IV) have been synthesized by the diphenyldichlorosilane with the Schiff bases derived from the condensation of heterocyclic ketones and aldehydes with a series of sulpha drugs. Their structures have been inferred on the basis of elemental analysis, UV, IR, and NMR spectral studies. The monomeric and nonelectrolytic nature of these compounds have been confirmed by molecular weight determinations and conductance measurements. The Schiff bases and their silicon complexes also have been screened for their antimicrobial activities against several fungi and bacteria and were found to be quite active in this respect.