Direct intramolecular amination of tryptophan esters to prepare pyrrolo[2,3-b]indoles
2017
A metal-free iodine-catalyzed intramolecular amination has been developed for the practical synthesis of pyrrolo[2,3-b]indoles from readily available tryptophan esters. The transformation has been applied to a wide array of substrates and can be performed on gram scale under very mild conditions.
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