Investigating the role of the gastrointestinal microbiome in response to immune checkpoint inhibitors (ICIs) among patients (pts) with metastatic renal cell carcinoma (mRCC).

Anika Agarwal,Jennifer L. Modliszewski,Lauren Davey,Marco Reyes-Martinez,Daniella Runyambo,David L. Corcoran,Holly K. Dressman,Daniel J. George,Raphael H. Valdivia,Andrew J. Armstrong,Tian Zhang

Investigating the role of the gastrointestinal microbiome in response to immune checkpoint inhibitors (ICIs) among patients (pts) with metastatic renal cell carcinoma (mRCC).

2020

Anika Agarwal
Jennifer L. Modliszewski
Lauren Davey
Marco Reyes-Martinez
Daniella Runyambo
David L. Corcoran
Holly K. Dressman
Daniel J. George
Raphael H. Valdivia
Andrew J. Armstrong
Tian Zhang

730Background: ICIs are effective in mRCC, but one pertinent clinical need is to identify predictive biomarkers for response. The PD-1 receptor has been implicated in regulating gastrointestinal co...

Keywords:

Pathology
Cancer research
Gastrointestinal Microbiome
Immune checkpoint
Renal cell carcinoma
Medicine
predictive biomarker
immune checkpoint inhibitors
Receptor

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