The advance on the mechanism of traditional Chinese medicine in treating psoriasis vulgaris of blood-heat syndrome

Epidemiology shows that the most common psoriasis is psoriasis vulgaris. The common traditional Chinese medicine (TCM) syndrom is the blood-heat type, which is equivalent to the progressing stage of psoriasis. This article summarized the experimental research of TCM in treating psoriasis vulgaris which is considering as the blood-heat type on the basis of the differentiation of symptoms and signs. The mechanism of clinical efficacy on treating psoriasis vulgaris which is at the blood-heat type was explained in different layers such as Th lymphocytes subgroups, Notchsignalpathway, PTH and hemorheology. This study aimed to help scholars to understand the mechanism of therapeutic effect of TCM on the treatment of psoriasis vulgaris. Key words: Psoriasis vulgaris; Blood-heat type; Traditional Chinese medicine; Mechanism; Review