Abstract 214: Risk and Risk Factors of Perioperative Myocardial Infarction After Carotid Endarterectomy and Carotid Angioplasty and Stenting: Systematic Review and Meta-analysis

Background and purpose: Carotid Angioplasty and Stenting (CAS) is associated with higher risk of periprocedural stroke and death compared with carotid endarterectomy (CEA). By contrast, the risk of myocardial infarction (MI) was higher after CEA than after CAS in randomized trials. However, numbers were small and risk factors are unknown. We therefore aimed to estimate the 30-day absolute risk of periprocedural MI after CAS and CEA and to determine which subgroups are at higher risks. Methods: We performed a systematic review and a meta-analysis of studies published from 01/1980 to 06/2014 and also collected unpublished data. We selected observational and randomized studies with data available on MI in at least one subgroup. We calculated pooled absolute and relative risks and identified differential effects on risks of MI (CAS vs CEA) with interaction tests using meta-regressions. Results: The 30-day absolute risk of MI after CEA was 0.82% (95%CI, 0.67-0.99; 66 studies, 75191 patients) and 0.64% (95%CI, ...