Antibiotic Susceptibility and Functional Group Characterization of Pinna nobilis Metabolites Against Clinical Isolates

AbstractThe present study was conducted to extraction and evaluation of antimicrobial potential and functional groups characterization of Pinna nobilis extract against clinical isolates such as Escherichia coli, Staphylococcus aureus, Bacilus subtilis, Vibrio Harvey and Aeromonas hydrophilla. The better antimicrobial activity results showed 10 to 12 mm at 750 µg/ml against E. coli, V. harvey and A. hydrophilla. Whereas the S. aureus and B. subtilis showed no antibacterial effect. The minimum inhibitory concentration (MIC) was recorded as 500 µg/ml against three tested bacterial strains. But minimal bactericidal effect was noted for V. harvey at 500 µg/ml, E. coli 500 µg/ml and A. hydrophilla respond the bactericidal effect at 700 µg/ml. The presence of biologically active functional groups in crude methanolic extracts showed Alkynes (C-H), phenyl ring (C-H), Carboxylic, ethers, Alcohols (C-O), Nitro (NO2), Amines (C-N), Nitriles (Ca”N) and Hydrogen bonding (O-H) Monomeric alcohols. The present finding con...