Pathophysiology and principles of management of the diabetic foot

Diabetic foot complications are the main cause of non-traumatic lower limb amputation internationally. Most amputations in diabetes are preceded by foot ulceration. Therefore, a thorough understanding of the causes, assessment and management of ulceration is essential. This chapter provides a concise description of the key factors contributing to the pathophysiology of the diabetic foot. The chapter also outlines an evidence-based approach to the clinical assessment and management based on recently published guidelines.