A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19

2016 
Introduction: the majority of parvovirus b19 infections are asymptomatic. In childhood, however, they may present as the fifth disease and in adults their manifestations can vary from mild, non-specific, cold-like symptoms to other forms of presentations. Papular-purpuric gloves and socks syndrome (PPGss) is an uncommon form of parvovirus b19 infection, characterized by symmetric, pruriginous and painful erythema and edema of feet and hands. Generally, systemic symptoms are usually mild and dissemination to other body regions occurs in only 50% of the cases. the rash gradually progresses to petechiae and purpura delineating well demarcated “socks” and “gloves” on both feet and hands. the diagnosis is predominantly based on the clinical features. serologic conversion is not considered as evidence of parvovirus b19 infection and histopathological findings from lesional skin are not specific. there are no definite antiviral
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