Increased Expression of L-Type Calcium Channels in Vascular Smooth Muscle Cells at Spastic Site in a Porcine Model of Coronary Artery Spasm

Summary:Coronary artery spasm is caused primarily by increased contractility of vascular smooth muscle. Excessive Ca2+ entry into vascular smooth muscle cells (VSMCs) may be one of the key mechanisms for the spasm, but no study has ever directly examined the possible alterations of Ca2+ channels in