Abstract 278: A Randomized, Blinded Trial of 100% Oxygen vs. Room Air During Cardiopulmonary Resuscitation in a Large Animal Model of Pediatric Cardiac Arrest

Alexandra M Marquez,Ryan W. Morgan,Michael Karlsson,Tiffany Ko,William P. Landis,Constantine D. Mavroudis,Jonathan Starr,Yuxi Lin,Timothy W. Boorady,Mahima Devarajan,Vinay Nadkarni,Robert A. Berg,Daniel J. Licht,Robert M. Sutton,Todd J. Kilbaugh

Abstract 278: A Randomized, Blinded Trial of 100% Oxygen vs. Room Air During Cardiopulmonary Resuscitation in a Large Animal Model of Pediatric Cardiac Arrest

2018

Alexandra M Marquez
Ryan W. Morgan
Michael Karlsson
Tiffany Ko
William P. Landis
Constantine D. Mavroudis
Jonathan Starr
Yuxi Lin
Timothy W. Boorady
Mahima Devarajan
Vinay Nadkarni
Robert A. Berg
Daniel J. Licht
Robert M. Sutton
Todd J. Kilbaugh

Introduction: Guidelines recommend CPR with 100% oxygen, but its effect on the pediatric brain is unknown. Hyperoxia during CPR may lead to significant oxidative injury from mitochondrial-derived r...

Keywords:

Anesthesia
Hyperoxia
large animal
oxidative injury
pediatric brain
Oxygen
Room air distribution
Cardiopulmonary resuscitation
Medicine

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