Probing the functional limits of the norepinephrine transporter with self-reporting, fluorescent stilbazolium dimers
2012
A series of stilbazolium dimers were synthesized and investigated as sterically demanding ligands targeting the norepinephrine transporter (NET). The environmentally sensitive fluorescence of the dyes enables their use as self-reporting ligands; binding to and displacement from NET can be monitored by fluorescence microscopy.
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