Reaction of Amines and Their Utilization. III.
1975
Authors found that N-acylethylenediamines obtained by the reactions of the methyl esters of C812 fatty acids with ethylenediamine readily cyclizes on heating to yield 2-alkyl 4, 5-dihydroimidazoles. The following results were also obtained with this finding.The type of the principal product obtained from the reaction between the methyl ester of a fatty acid with ethylenediamine in ethanol was dependent on the method of separation of the reaction product; namely, the solvent extraction afforded the N-acylethylenediamine and the distillation under reduced pressure afforded 2-alkyl-4, 5-dihydroimidazol.
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