Characteristics of computed tomography perfusion parameters in non-small-cell-lung-cancer and its relationship to histology, size, stage an treatment response

Abstract Objectives To analyze computed tomography perfusion (CTP) parameters in NSCLC. Materials and methods Prospective study, 152 patients with NSCLC. CTP parameters were correlated with histology, stage, size and response to conventional chemotherapy/radiotherapy. Results Neuroendocrine tumours presented higher BV (p 0.002). Negative correlation of PMB (p 0.003) and positive of MTT (p 0.046) with T stage was found. BF showed negative correlation with size. No differences were found with the RECIST levels of response to chemotherapy/radiotherapy. Conclusions CTP parameters were highly variable. Neuroendocrine tumours presented higher BV and PMB values. Perfusion parameters do not differ depending on the stage and do not predict response to treatment.