Clinical significance of non-Hodgkin's lymphoma with an irregular, non-contrast-enhanced area

Background An irregular, non-contrast-enhanced area shown on postcontrast computed tomography (CT) or postcontrast magnetic resonance imaging (MRI) in cases of non-Hodgkin's lymphoma (NHL) may indicate that the primary tumor has a high degree of malignancy. This study was planned to determine whether this indicated a poor prognosis.