Pummerer rearrangement using bis(p-nitrophenyl) phosphorazidate as an azidation reagent: A novel synthesis of azidomethyl sulfides

Abstract A novel method for the synthesis of azidomethyl sulfides by Pummerer rearrangement using bis( p -nitrophenyl) phosphorazidate ( p -NO 2 DPPA) as an azidation reagent was developed. Various methyl sulfoxides were converted into the corresponding azidomethyl sulfides. Importantly, this reaction enables the preparation of azidomethyl sulfides without the use of toxic or explosive azide sources.