Fahr hastalığı; iki olgu sunumu
2013
Fahr hastaligi; bazal ganglionlar, serebellar dentat nukleus ve beyaz cevherde bilateral ve hemen daima simetrik olarak kalsiyum ve diger minerallerin depolandigi nadir bir hastaliktir. Klinik bulgular siklikla parkinsonizm, distoni, tremor, kore, ataksiye ek olarak demans ve duygu durum bozukluklaridir. Fahr sendromu paratiroid bozukluklar basta olmak uzere degisik metabolik bozukluklara ve beraberinde sistemik hastaliklara bagli olarak ortaya cikabilir. Bu makalede, unutkanlik ve epilepsi yakinmalari ile hastanemize basvuran, ayirici tanida sistemik ve metabolik hastaliklar saptanan ve kraniyal bilgisayarli tomografi incelemesinde her iki bazal ganglionlarda, talamuslarda, periventrikuler beyaz cevherde, sentrum semiovalede ve serebellumda cok sayida kalsifiye alanlar izlenen 66 ve 68 yasindaki bayan hastalar sunulmustur.
Fahr’s disease; two case report
Fahr’s disease is a rare disorder where bilateral, almost symmetric, calcium and other mineral deposits occur in basal ganglia, cerebellar dentate nucleus and white matter. Common
clinical findings of the disease are characterizing parkinsonism, dystonia, chorea, ataxia and psychiatric symptoms. Fahr’s syndrome is associated with various metabolic and systemic disorders, specially parathyroid disorders. In this article we described 66 and 68 years old two female patients who have memory loss, epilepsy, different systemic and metabolic diseases. Brain computed tomography showed Fahr type calcification in the bilateral basal ganglia, thalamus, periventricular white matter, centrum semiovale,
and cerebellum.
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