Antiangiogenic Therapies for Mesothelioma: What Is the Role in Mesothelioma Treatment?

Malignant pleural mesothelioma is known for its correlation between angiogenic factors and survival. In this chapter, we focus on the background of this phenomenon and present the available data of studies with antiangiogenic agents. To date, only limited signals have been found that interventions using these agents are of great impact of the disease. It is concluded that single-agent approaches are futile and should be tested in combination with chemotherapy or in a multimodality setting.