Kaposi's sarcoma after renal transplantation.

To the Editor: Cancer after transplantation has long been recognized to be a risk associated with immunosuppression, but Kaposi's sarcoma is a rare tumor in this situation.1 A 39-year-old man with end-stage renal disease received an allograft from a living related donor in 1992. He was receiving steroids, azathioprine, and cyclosporine and had stable renal function. Eighteen months after transplantation, a cluster of pigmented lesions appeared in his right calf. Histologic evaluation revealed an infiltrating spindle-cell tumor around eccrine ducts, with hyaline globules and hemosiderin among the slit-like vascular pores — features consistent with Kaposi's sarcoma (Figure 1). Repeated testing . . .