Propagation of mammalian viruses in Protista. III. Change in population densities, viability and multiplication of yeasts and tetrahymena experimentally infected with encephalomyo-carditis virus

Abstract Adsorption and presence of fluorochrome labelled Encephalomyocarditis (EMC) virus was visualized in the yeast, S. Cerevisiae f. and the Ciliate, T. pyriformis, g. (1). The multiplication of complete EMC particles and the resynthesis of Poliovirus from isolated infectious RNA was also demonstrated in Protista (2). The present report is concerned with the cytophathic effect (CPE) of the virus infection consisting of decrease in population densities, change in size, shape, viability and multiplication of Saccharomyces, Candida and Tetrahymena cells incubated with EMC. Further, mainly cytological aspects will be described separately (3).