A Randomized Comparison for Two Hemostasis after Cardiac Catheterization Via Femoral Artery

Objective:To compare the safety and efficacy of vascular closure device (VCD) with manual compression (MC) in achieving hemostasis after femoral cardiac catheterization patients and to determine the ability of these two techniques to reduce groin complications and discomfort.Methods:A total of 200 patients were randomly divided into VCD (group A,n=100) versus MC (group B,n=100). The success rate of hemostasis, the time of hemostasis, of bandaging with compression, of immobilization and the complication rates were observed.Results:Technical success rate (group A 95% vs.87%), the time of hemostasis (group A 3.19 min±1.64 min vs. 18.71 min±6.87 min), of bandaging with compression (group A 0h vs. 6.08 h±2.43 h), of immobilization (group A 2.92 h±1.42 h vs.21.4 h±2.5 h) all were significantly different between the two groups (P0.001). There were low rate of complication including merely 5% (vs.11%) of the hematomas, 2% (vs.8%) of vasovagal reflex in the group A. There were 5% of pseudoaneurysm, of and 92% of distress on the waist and lower limb.Conclusion:This vascular closure device provideed a safe and effective means of obtaining rapid arterial hemostasis after cardiac catheterizatio. It appeared to be particularly useful in patients most at risk for access site complications or patients unable to tolerate laying for a long time.