Effects of different intensity pulsed electromagnetic fields on serum estradiol of ovariectomized rats

Objective To explore the effects of different intensity pulsed electromagnetic fields(PEMFs) on serum estradiol in ovariectomized rats.Methods Fifty female SD rats were randomly divided into five groups: sham-operated control(no PEMF treatment),ovariectomized control(no PEMF treatment),ovariectomized group Ⅰ,Ⅱ,Ⅲ(PEMF treatment at 8 Hz frequency and 0.77 mT,3.82 mT,9.87 mT intensity,40 min daily for 30 days).Except for the sham-operated control rats,a standardized ovariectomy was used on every rat of other groups.The serum estradiol(E2) of rats was assessed at 30 days after PEMF treatment.Results The E2 values of the SHAM control group were significantly higher than those of other four groups(P0.05 or P0.01),but the difference in E2 values was not significant among the other four groups(P0.05).Conclusion PEMFs can not improve the serum estradiol level of ovariectomized rat,it shows that the therapeutical effect of PEMFs is not due to improve the serum estradiol level.