Promising approach to the synthesis of unknown 2-(2, 2′-diamino-4,5′-dipyrimidin-6-yl)phenols(naphthols) and 2-amino-6-(2-hydroxyphenyl)-4-(4-nitrophenyl)nicotinonitriles

Novel derivatives of 2-(2,2′-diamino-4,5′-bipyrimidin-6-yl)phenols(naphthols) were obtained in the reaction of (4-amino-2H-(benzo[g])chromen-2-ylidene)malondialdehyde with 1,3-dinucleophile proceeding as a cascade reaction initiated by the Michael reaction. It has been established that the recyclization of 2-aryl-4H-chromen-4-imines under the influence of malononitrile as C-nucleophile is completed by the formation of 2-amino-6-(2-hydroxyphenyl)-4-(4-nitrophenyl)nicotinonitrile by the 6-exo-trig-cyclization mechanism.