Organotin(IV) complexes of Schiff bases derived by condensation of heterocyclic ketones and sulfa drugs

Abstract —Reaction of bis(triorganotin)oxide with Schiff bases derived by condensation of heterocyclic ketones, 2-acetylfuran and 2-acetylthiophene, with various sulfadrugs (sulfaguanidine, sulfathiazole, sulfisoxazole and sulfadiazine) leads to the formation of a new series of organotin(IV) complexes. An attempt has been made to probe their structures on the basis of elemental analysis, conductance measurements, molecular weight determination, UV, IR and NMR (1H, 13C and 119Sn) spectral studies. The results of antimicrobial effects of some representative complexes on different species of pathogenic fungi and bacteria have also been recorded and discussed.