Leptomeningeal metastasis of uterine cervical cancer 17 years after primary tumor treatment.

Leptomeningeal metastasis (LM) occurs in 3–8% of cancer patients 1, 2. In most cases, LM develops secondary to lung, breast, gastrointestinal, or hematopoietic malignancies, or malignant melanoma 3. LM from gynecologic malignancies is rare, and when present, it is associated with ovarian cancer 4. LM of uterine cervical cancer is extremely rare. Yust et al. 5 reported that 0.03% (4/13289) of cervical cancer cases registered in the MD Anderson Cancer Center database developed LM. Here, we report a unique case of LM of uterine cervical cancer presenting with ptosis due to oculomotor nerve invasion 17 years after treatment of the primary tumor.