Novel Methods for Syntheses of Substituted Oxazoles by Cyclization of Vinyl Bromides.

Jagabandhu Das,Joyce A. Reid,David R. Kronenthal,Janak Singh,Paul D. Pansegrau,Richard H. Mueller

Novel Methods for Syntheses of Substituted Oxazoles by Cyclization of Vinyl Bromides.

1993

Jagabandhu Das
Joyce A. Reid
David R. Kronenthal
Janak Singh
Paul D. Pansegrau
Richard H. Mueller

Abstract Several methods for converting vinyl bromides and vinyl dibromides to oxazoles are described. Cyclization of vinyl bromide 6 with cesium carbonate in dioxane forms oxazole 7 while 6 is converted to the corresponding bromooxazole 12 by treatment with CuBr 2 /DBU.

Keywords:

Organic chemistry
Chemistry

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