Relationship between Pretreatment Electroencephalographic Coherence Measures and Subsequent Response to Electroconvulsive Therapy: A Preliminary Study

Quantitative analyses of EEG recordings taken prior to a course of ECT in elderly depressed patients showed that normal anterior interhemispheric coherence in the delta frequency band was associated with more favorable clinical response to ECT, whereas lower coherence values were associated with incomplete therapeutic response. Clinical implications of these findings are discussed.