КЛИНИКО-ЛАБОРАТОРНЫЕ ПРОЯВЛЕНИЯ ХРОНИЧЕСКОГО ПИЕЛОНЕФРИТА НА ФОНЕ НЕФРОЛИТИАЗА, СОЧЕТАЮЩЕГОСЯ С АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ

THE AIM OF RESEARCH was to study clinical and laboratory manifestations of chronic pyelonephritis (ChrPN) with arterial hypertension at the stage of remission. PATEINTS AND METHODS. More than 120 patients were observed with (ChrPN) associated with kidney stone disease (KSD) and dysmetabolic nephropathy (DN) at clinical and laboratory remission. At 60 patients at the age of 18-59 years ChrPN was associated with arterial hypertension (AH). For patients investigation we were used clinical, laboratory, instrumental and special biochemical diagnostic methods. Latest methods included study of lipid peroxidation processes, alpha tocopherol lipid soluble antioxidant level, general phospholipids and cholesterine in membranes of polymorphonuclear leucocytes (PML). RESULTS. It was revealed that in patients with ChrPN associated with nephrolithiasis and DN on clinical and laboratory remission are registered: different manifestations of asthenovegetative syndrome, increase of left ventricular mass index (LVMI) is discovered, lipid peroxidation processes activity alteration is revealed associated with decrease of antioxidant protective function in membranes of neutrophils with domination of intensity of these disorders in group with symptomatic arterial hypertension. CONCLUSION. As a result undertaken studies represent maintenance of clinical and laboratory manifestations of disease even on remission, which demand continuation of remedial measures for patients on clinical and laboratory remission of ChrpN associated with AH.