TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity

Junyoung Lee,Eunjin Lee,Sung-Wook Hong,Daeun Kim,Eunju O,Jonathan Sprent,Sin-Hyeog Im,You Jeong Lee,Charles D. Surh

TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity

2019

Junyoung Lee
Eunjin Lee
Sung-Wook Hong
Daeun Kim
Eunju O
Jonathan Sprent
Sin-Hyeog Im
You Jeong Lee
Charles D. Surh

ABSTRACTIL-2 is a pleiotropic cytokine that plays an essential role in the survival, expansion, and function of CD8 T cells, regulatory T cells (Tregs), and natural killer (NK) cells. Previous stud...

Keywords:

IL-2 receptor
Immunotherapy
Immunology
Cytokine
Immunity
Cancer research
Cytotoxic T cell
Interleukin 2
Medicine
Antibody
Natural killer cell
Cell growth

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations