LB02.04: GASTRIN AND D1 DOPAMINE RECEPTOR INTERACT TO INDUCE NATRIURESIS AND DIURESIS.

Objective:Oral NaCl intake produces stronger natriuresis and diuresis than venous infusion of the same amount NaCl, indicating the potential existence of renal-gastric axis. Gastrin, from gastrointestinal tract, is dominant one due to its natriuretic effects and taken-up by the renal proximal tubule