Trombosis venosa cerebral en adultos en el Complejo Hospitalario-Universitario de A Coruña España. Revisión clínico-radiológica de 48 casos diagnosticados entre 1995 Y 2005

2010 
RESUMEN INTRODUCCION: La trombosis venosa cerebral es una patologia del sistema nervioso central cuya incidencia es aun desconocida. El diagnostico es dificil, teniendo en cuenta que las manifestaciones neurologicas asi como su etiologia pueden ser extremadamente variables.  OBJETIVOS: conocer la etiologia, clinica y pronostico de las trombosis de los senos venosos cerebrales en el Complejo Hospitalario Universitario Juan Canalejo de A Coruna. Pacientes y metodos: se revisaron de forma retrospectiva los casos diagnosticados de TVC desde 1995 a 2005. Se registro la etiologia, las manifestaciones clinicas, los signos radiologicos en la TAC en el momento del ingreso, el tratamiento aplicado y el pronostico a los 6 meses empleando la escala modificada de Rankin.  RESULTADOS: se registraron 48 casos de los cuales 27 eran mujeres y 21 hombres; el rango de edad fue de 21 a 88 anos, con una mediana de 43 anos. La etiologia infecciosa estuvo presente en cinco casos equivalente al (10,4%). En pacientes jovenes ( CONCLUSIONES: en pacientes jovenes predomina la etiologia por anticonceptivos y los trastornos de la coagulacion, en cambio, a partir de la sexta decada dominan las neoplasias subyacentes y causas indeterminadas. El tratamiento anticoagulante es eficaz y seguro. El pronostico es excelente en la mayoria de los casos.  Palabras clave: Trombosis venosa cerebral. Senos durales. Ictus. Anticoagulantes. Heparina. Pronostico. ABSTRACT INTRODUCTION: Central venous trombosis in adults in the complejo hospitalario-universitario de A Coruna Spain. Clinic-radiology review of 48 cases between 1955 and 2005. Introduction. Cerebral venous thrombosis is a pathology of the central nervous system which incident is still unknown. The diagnosis is difficult because the neurological manifestations and its etiology may be extremely varied.  OBJECTIVES: The aim of our study was to ascertain the etiology, the clinical manifestations and the prognosis of the cases of Cerebral venous thrombosis diagnosed at our Hospital. Patients and Methods. It was reviewed retrospectively all histories of the patients who were diagnosed of cerebral venous thrombosis from 1995 to 2005. It was recorded the etiological factors, the clinical manifestations, the radiological signs in the computed tomography scan at admission, the treatment administered and the prognosis at six months was classified in accordance with the modified Rankin scale (mRS).  RESULTS:  We reviewed 48 cases (27 females; 21 males). The age range was 21 to 88 years old, with a median at 43 years. The infectious etiology was present in five patients (10,4%). In the young group ( CONCLUSIONS: In young population, the most frequently etiologies are contraceptives and coagulation disease and in people older than 60 years, the underlying neoplasm and cases of unknown etiology prevail. The anticoagulant treatment is effective and safe. The prognosis was excellent in the most of the cases.  Key words: Cerebral venous thrombosis. Venous sinuses. Stroke. Anticoagulant. Heparin. Prognosis.
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