Biological Activity of 4-Substituted Methoxybenzoyl- Aryl-Thiazole: An Active Microtubule Inhibitor

Chien-Ming Li,Zhao Wang,Yan Lu,Sunjoo Ahn,Ramesh Narayanan,Jeffrey D. Kearbey,Deanna N. Parke,Wei Li,Duane D. Miller,James T. Dalton

Biological Activity of 4-Substituted Methoxybenzoyl- Aryl-Thiazole: An Active Microtubule Inhibitor

2011

Chien-Ming Li
Zhao Wang
Yan Lu
Sunjoo Ahn
Ramesh Narayanan
Jeffrey D. Kearbey
Deanna N. Parke
Wei Li
Duane D. Miller
James T. Dalton

SMART compounds are as efficacious as currently approved antitubulin drugs for cancer treatment, but unlike these drugs they can circumvent P-glycoprotein-mediated drug resistance.

Keywords:

Drug resistance
Thiazole
Aryl
Biological activity
Microtubule Inhibitor
Immunology
Microtubule
Medicine
Pharmacology
cancer treatment

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