Oxidative injury as contributory factor for red cells storage lesion during twenty eight days of storage.

Background Storage of red blood cells at 4 °C is associated with deleterious metabolic and biochemical changes, collectively referred to as “storage lesions”. Lipid peroxidation of the red cell membrane leading to lysis contributes to these storage lesions. The aim of the present study was to investigate oxidative injury to red cells during storage for 28 days and its correlation with markers of red cell membrane damage.