Assessment of Prophylactic Antibiotic Prescription Pattern in Elective Surgery Patients in Accordance with National and International Guidelines

Abstract Objective Prophylactic antibiotics are administered preoperatively to reduce the incidence of surgical site infection. The aim of this study was to determine the pattern of administration of prophylactic antibiotic among elective surgery patients in accordance with national and international guidelines. Method This retrospective descriptive was conducted on the patients who underwent elective surgery at (XXX) Educational and Medical Center. Patients’ file was used to obtain the following data: demographic information including patients' age and gender, prescribing prophylactic antibiotics, type, dose and time of administration with the indications mentioned in the guidelines for prevention of SSI of the World Health Organization (2017) and the instructions of the Ministry of Health and Medical Education of Iran compared. Data were analyzed using SPSS statistical program. Result The time, type, dose, duration and intervals of prophylactic antibiotic administration in the present study were 64.8%, 42.5%, 36%, 52.8% and 32%, respectively, according to national guidelines and were 58.8%, 40%, 31.5%, 45.5% and 28%, respectively, according to international guidelines. Administration of prophylactics in terms of time dose, duration and intervals in accordance with national and international guidelines were not associated with the type of surgery, p  Conclusions The results of the present study showed that the type, duration and intervals of prophylactic antibiotic administration varies in accordance national and international guidelines. Further studies are required to determine the effects of these parameters under national and international guideline on postoperative outcomes like surgical site infection.