Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial

Stephen Pj Macdonald,Gerben Keijzers,David Taylor,Frances Kinnear,Glenn Arendts,Daniel M Fatovich,Rinaldo Bellomo,David McCutcheon,John F. Fraser,Juan Carlos Ascencio-Lane,Sally Burrows,Edward Litton,Amanda Harley,Matthew Anstey,Ashes Mukherjee

Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial

2018

Stephen Pj Macdonald
Gerben Keijzers
David Taylor
Frances Kinnear
Glenn Arendts
Daniel M Fatovich
Rinaldo Bellomo
David McCutcheon
John F. Fraser
Juan Carlos Ascencio-Lane
Sally Burrows
Edward Litton
Amanda Harley
Matthew Anstey
Ashes Mukherjee

Purpose To determine if a regimen of restricted fluids and early vasopressor compared to usual care is feasible for initial resuscitation of hypotension due to suspected sepsis.

Keywords:

Septic shock
Randomized controlled trial
Intensive care medicine
Resuscitation
Regimen
Sepsis
Medicine
Emergency department
Prospective cohort study
Anesthesia
Blood pressure

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