SACUBITRIL/VALSARTAN VERSUS ENALAPRIL IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION: FINDINGS FROM AWAKE-HF, A RANDOMIZED, CLINICAL TRIAL USING A WEARABLE BIOSENSOR

The AWAKE-HF trial evaluated the effect of sacubitril/valsartan (S/V) vs enalapril on daytime activity and sleep in patients with heart failure with reduced ejection fraction (HFrEF), using actigraphy. After a 2-week baseline period and 36-hour washout, individuals 18 to 80 years of age with New