Solvent-free one-pot synthesis and crystal structure of a spiro[indole-thiazine]

An improved facile one-pot synthesis of 3′-(fluorophenyl)-spiro[3H-indole-3,2′-tetrahydro-1,3-thiazine]-2,4′(1H)-dione is reported using an environmentally friendly green chemistry procedure under microwave irradiation. The crystal structure of the reported compound has been determined by a X-ray diffraction. The molecule is largely planar and has cell parameters of a = 11.181(9) A, b = 11.06(1) A, c = 12.715(12) A, α = 90°, β = 98.31(7)°, γ = 90°.