Dyslipidemia in diabetes patient is responsible for developing nephritic syndrome with increasing ages, a survey based cross sectional study.

Objectives: The objective of this study was to evaluate the level of lipid profile and serum creatinine in patients with diabetes mellitus to correlate the lipid profile abnormalities with serum creatinine levels in diabetic patients. Methods: This cross sectional health survey was carried out with a self-designed standard questionnaire by manual data collection over a six months period (12.09.2015 to 10.04.2016) at three adjacent cities Jessore Sadar, Jhikargacha and Chowgacha upazila respectively. The data were collected from the patients prescription, diagnostic reports and by directly interviewing the patients who were treated as either type 1 or type 2 diabetic 235 fasting patients during the study period. Descriptive statistics were applied to the collected data and analyzed using Microsoft Excel software. Results: In our current survey, the average levels of HDL, LDL, TC, TG and Serum creatinine of investigated patients were observed with respect to their individual groups as for Group A - 40 mg/dl, 110 mg/dl, 220 mg/dl, 135 mg/dl and 0.8 mg/dl; Group B - 40 mg/dl, 150 mg/dl, 320 mg/dl, 290 mg/dl and 1.1 mg/dl; Group C - 38 mg/dl, 180 mg/dl, 210 mg/dl, 388 mg/dl and 1.25 mg/dl; Group D - 32 mg/dl, 190 mg/dl, 240 mg/dl, 435 mg/dl and 1.00 mg/dl. 39.13% male and 35.29% female patients with type 1 DM, whereas 85.25% male and 82.19% female patients with type 2 DM, containing dyslipidemia was seen. Being prone to develop dyslipidemia, the patients with uncontrolled lipid profile abnormalities are among the highest risk to develop diabetic nephropathy characterized by elevated levels of serum creatinine followed by reduced glomerular filtration rate (GFR). Conclusion: This study revealed the interesting outcome is like that, diabetes mellitus patients are more prone to increasing bad cholesterol and creatinine levels in serum and these levels are found to increase with their age as well. Since lipid profile abnormalities, mainly dyslipidemia is inextricably linked with increased serum creatinine level as well as developing diabetic nephropathy, especial attention should be given for controlling hyperglycemia owing to avoid associated cardiovascular complications.