HPLC analytical method for chirality purity of 2-amino butanol

The invention belongs to the technical field of pharmaceutical analysis and specifically relates to a HPLC (High Performance Liquid Chromatography) analytical method for chirality purity of 2-amino butanol. The method comprises the following steps: by taking R-alpha-methyl-2-naphthalene acetylchloride as a derivatization reagent, performing quick double-derivatization reaction with 2-amino butanol, generating ultraviolet absorption ramifications, and then determining the nature, quantity and chirality purity of 2-amino butanol by using HPLC and ultraviolet. According to the method, the derivatization reaction is quick and mild in reaction conditions; the detection sensitivity is high; the repeatability is excellent; the method can be used for effectively detecting the chirality purity of 2-amino butanol; the standardizing operation is easily performed; the method has practical application value and practical significance.