Patient-reported outcomes, emoji, and activity measured on the Apple Watch in cancer patients.

6501Background: Patient-reported outcomes (PROs) are important measures in patients with cancer, but may be burdensome to collect. We aimed to measure PROs via mobile technology, using novel emoji PRO scales and associations between PROs and wearable data. Methods: Adult patients (pts) with diagnosis ( 6 months, and ownership of an iPhone ≥5.0 were recruited and provided with an Apple Watch. Pts completed baseline and weekly PROs for 12 weeks: PROMIS physical function, fatigue, sleep, social/role function short forms; single-item linear analog self-assessment (LASA) of quality of life (QOL), fatigue, and physical function. Pts were randomized into 3 groups for mode of survey response: paper, iPhone, and Watch. Watch and iPhone groups completed an emoji mood scale and an emoji ordinal scale for physical, emotional, and overall QOL. Activity levels were analyzed using the square root of the average daily val...