A CLINICAL STUDY OF EFFICACY OF PROPHYLACTIC V/S EMPIRICAL ANTIBIOTIC USAGE IN CLEAN AND CLEAN CONTAMINATED GENERAL SURGICAL PROCEDURES

It is a prospective study carried out on patients who underwent clean and clean contaminated elective general surgical procedures from June 2012 to May 2014 at Govt. General Hospital, Kakinada, East Godavari District of Andhra Pradesh. Patients with diabetes mellitus, Patients on steroids, chemotherapy, and immunosuppression are excluded. Total of 100 cases were studied.50 cases of clean and 50 cases of clean contaminated procedures were selected. Out of 50 cases of clean procedures 25 were given prophylactic and 25 were given empirical antibiotics. Out of 50 cases of clean contaminated cases 25 were given prophylactic and 25 were given empirical antibiotic. Data analysis was done with SPSS software. To present the results mean+SD was used and a 'P' value of 0.05, which was not significant. CONCLUSION: Thus it can be concluded from this study that a single dose antibiotic prophylaxis prior to surgery is sufficient to prevent post- operative surgical site infections in clean and clean contaminated surgeries thus preventing adverse outcomes of inadvertent antibiotic usage, such as multi-drug resistance and drug toxicity, financial burden on the hospital can be decreased,work load on junior doctors can be reduced.