Association of μ-Opioid Receptor Gene Polymorphism A118G with Alcohol Dependence in a Japanese Population

Daisuke Nishizawa,Wenhua Han,Junko Hasegawa,Takafumi Ishida,Yukio Numata,Tadahiro Sato,Atsuko Kawai,Kazutaka Ikeda

Association of μ-Opioid Receptor Gene Polymorphism A118G with Alcohol Dependence in a Japanese Population

2006

Daisuke Nishizawa
Wenhua Han
Junko Hasegawa
Takafumi Ishida
Yukio Numata
Tadahiro Sato
Atsuko Kawai
Kazutaka Ikeda

Ethanol is considered to activate the brain reward system by increasing the release of an endogenous opioid receptor ligand, β-endorphin. The polymorphism A118G in the µ-opioid receptor gene

Keywords:

Endocrinology
Psychology
Internal medicine
Gene polymorphism
Endogeny
Ethanol
Polymorphism (computer science)
Opioid receptor
Alcohol dependence
Population
Pharmacology
Receptor
endogenous opioid
Gene

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