Cladosiphon okamuranus hyaluronidase derived inhibitor or atopic dermatitis therapeutic agent

An object of the present invention is to provide a hyaluronidase inhibitor or a therapeutic agent for atopic dermatitis that uses fucoidan from an extract of seaweed as an active ingredient and uses its physiological activity. The present invention provides a hyaluronidase inhibitor or a therapeutic agent for atopic dermatitis comprising acetylfucoidan obtained from Okinawa mozuku or its sulfate as an active ingredient. This acetyl fucoidan is obtained by extracting Okinawa mozuku with a dilute hydrochloric acid aqueous solution or the like. [Selection] Figure 1