Aripiprazole : Pharmacodynamics of a dopamine partial agonist for the treatment of schizophrenia
2006
Aripiprazole is the first approved atypical antipsychotic with a mechanism of action that exerts a partial agonism with high affinity at Dopamin D 2 - and Serotonin-5-HT 1A -receptors as well as an antagonism at Serotonin-5-HT 2A -receptors. Aripiprazole provides good clinical effectiveness and a favorable profile of safety and tolerability. The special pharmacodynamics of aripiprazole are described herein.
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