Use of MR Cell Tracking to Evaluate Targeting of Glial Precursor Cells to Inflammatory Tissue by Exploiting the Very Late Antigen-4 Docking Receptor

Intraarterial image-guided delivery of cells overexpressing the docking molecule very late antigen-4 proved to be an effective strategy for widespread targeting of cells to inflammatory brain tissue, which can be monitored in a clinically applicable manner by using MR imaging cell tracking.